Provision of Sequencing Panel for Detection of Gene Fusions In Cancer

The All Wales Genomics Laboratory intends to procure an RNA sequencing panel to enable the identification of gene fusion events in somatic tissue samples, to replace the current laboratory tests. AWGL currently offers a range of gene fusion detection services using predominantly fluorescence in situ hybridisation (FISH) together with a limited number of qPCR assays. These tests cover the common genetic translocations seen in haematological malignancies, lymphomas, sarcomas and solid tumour referrals in a range of tissues including bone marrow, peripheral blood and formalin-fixed paraffin embedded (FFPE) tissues.